Her agent, John Grant, said Chambers died of natural causes. The British actress is survived by her husband, actor Ian Dunn.
“Over the years, Emma, created a wealth of characters and an immense body of work. She brought laughter and joy to many, and will be greatly missed," John Grant said.
Hugh Grant tweeted that Chambers was “a hilarious and very warm person and of course a brilliant actress.”
In addition to “Notting Hill,” Chambers starred for more than a decade as Alice Tinker in the BBC comedy “The Vicar of Dibley,” CNN reported.
Our beautiful friend Emma Chambers has died at the age of 53. We're very very sad. She was a great, great comedy performer, and a truly fine actress. And a tender, sweet, funny, unusual, loving human being. pic.twitter.com/vLQcRcv2Ex